'Senescence' is the state or process of aging. The word senescence is derived from the Latin word senex, meaing "old man" or "old age."
Cellular senescence refers to a phenomena where isolated cells demonstrate a limited ability to divide in culture. Organismal senescence refers to the aging of organisms.
Organismal aging is generally characterized by the declining ability to respond to stress, increasing homeostatic imbalance and increased risk of disease. Because of this, death is the ultimate consequence of aging.
Genetic and environmental interventions are known to affect the life span of model organisms. This gives many hope that human aging can be slowed or changed. Dietary calorie restriction, by 30 percent for example, extends the life span of yeast, worms, flies, mice, and monkeys. Several genes are known to be necessary for this extension, and modification of these genes is also sufficient to produce the same effect as diet.
Sleeping well at 100 years of age: Study searches for the secrets to healthy longevity PhysOrg - May 2, 2010
Facial Aging Is More Than Skin Deep Science Daily - April 20, 2010
7 Ways the Mind and Body Change With Age Live Science - April 5, 2010
Scientists solve aging puzzle PhysOrg - February 16, 2010
British scientists discover 'secret to aging' bringing new hope to old-age sufferers Telegraph.co.uk - February 16, 2010
Scientists said the discovery would unlikely provide an elixir of eternal life in the near future.
Genes reveal 'biological aging' BBC - February 8, 2010
Scientists identify first genetic variant linked to biological aging in humans PhysOrg - February 8, 2010
Can the Aging Process Be Slowed? Live Science - December 16, 2009
People who look young for their age 'live longer' BBC - December 15, 2009
Long-Lived Costa Ricans Offer Secrets to Reaching 100 National Geographic - April 14, 2008
'Long-life' genes found in 100-year-old humans New Scientist - March 3, 2008
Scientists can tell date of birth by looking into eyes Telegraph.co.uk - February 26, 2008
The towns where people live the longest BBC - February 20, 2008
Skin aging 'reversed' in mice BBC - November 30, 2007
The Mysteries of Mental Age Wired - February 8, 2007
Mayo Clinic Researchers Identify Gene Regulating Aging And Fertility Science Daily - July 2004
Longevity Evolved Late For Humans Science Daily - July 2004
A dramatic increase in human longevity took place during the early Upper Paleolithic Period, around 30,000 B.C.
Premature aging secret unlocked BBC - May 2004
Measuring the tiny mechanisms in cells which hold the key to aging revealed BBC - January 20, 2003
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