Ebola Virus Disease


Ebola virus disease (EVD) (or Ebola hemorrhagic fever (EHF)) is the name for the human disease which may be caused by any of four of the five known ebolaviruses. These four viruses are: Bundibugyo virus (BDBV), Ebola virus (EBOV), Sudan virus (SUDV), and Taï Forest virus (TAFV, formerly and more commonly Côte d'Ivoire Ebolavirus (Ivory Coast Ebolavirus, CIEBOV)). EVD is a viral hemorrhagic fever (VHF), and is clinically nearly indistinguishable from Marburg virus disease (MVD).

Ebola virus (EBOV) causes severe disease in humans and in nonhuman primates in the form of viral hemorrhagic fever. EBOV is a select agent, World Health Organization Risk Group 4 Pathogen (requiring Biosafety Level 4-equivalent containment), National Institutes of Health/National Institute of Allergy and Infectious Diseases Category A Priority Pathogen, Centers for Disease Control and Prevention Category A Bioterrorism Agent, and listed as a Biological Agent for Export Control by the Australia Group. Read more ...




In the News ...





Ebola 'Patient Zero': How Outbreak Started from Single Child   Live Science - October 30, 2014
When Ebola virus came for the first time to a small village in Guinea, the victim was a toddler, who later became known to the world as Patient Zero. He died on Dec. 6, 2013, at age 2, and the domino effect of his illness has spiraled into the outbreak currently ravaging three nations in West Africa. His name was Emile Ouamouno. Emile's 3-year-old sister, his mother and his grandmother all died by January, leaving his father behind. Ebola outbreak in Guinea 'unprecedented' - MSF   BBC - March 31, 2014
The Ebola outbreak that has killed 78 people in Guinea is "unprecedented", a medical charity has said. An official with Medecins Sans Frontieres (MSF) said the spread of the disease across the country made it very difficult to control. The West African state is facing a battle to contain the outbreak after cases were reported in areas that are hundreds of kilometres apart.




Ebola Virus Disarmed By Excising A Single Gene Science Daily - January 22, 2008
he deadly Ebola virus, an emerging public health concern in Africa and a potential biological weapon, ranks among the most feared of exotic pathogens. Due to its virulent nature, and because no vaccines or treatments are available, scientists studying the agent have had to work under the most stringent biocontainment protocols. Now, however, a team of researchers has figured out a way to genetically disarm the virus, effectively confining it to a set of specialized cells and making the agent safe to study under conditions far less stringent than those currently imposed.




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